Indigenous Knowledge Systems (IKS) encapsulate the accumulated wisdom, practices, beliefs, and cultural expressions of communities that have evolved over generations. In India, a country with vast ethnic, linguistic, and cultural diversity, indigenous knowledge plays a pivotal role in areas such as agriculture, medicine, biodiversity conservation, and craftsmanship. However, rapid modernization, globalization, and information technology advancements have both expanded opportunities and posed complex challenges in the preservation, documentation, and dissemination of these knowledge systems. This research article examines the multifaceted aspects of digital preservation of indigenous knowledge in India, exploring the conceptual foundations, technological interventions, methodological approaches, policy frameworks, case studies, and best practices. By synthesizing existing literature, analyzing current initiatives, and highlighting gaps, this article argues for a holistic, culturally sensitive, and participatory approach to digital preservation that safeguards intellectual property rights, fosters community engagement, and leverages appropriate digital technologies. The interplay between digital platforms, ethical considerations, and sustainable preservation strategies forms the backbone of the discourse. Furthermore, the study identifies key opportunities—such as community-driven digital archives, use of semantic technologies, and integration with educational systems—while addressing challenges including resource constraints, language barriers, and digital divide. Policy recommendations and future research avenues are presented to build a resilient ecosystem for the sustained transmission of indigenous knowledge in India