Published on: May 2026
DEVELOPMENT AND EVALUATION OF A NATURAL RESIN–WAX BASED HERBAL CHEWING GUM AS A BUCCAL IMMUNOMODULATORY DELIVERY SYSTEM
Shelly Badal
Sonia Sharma
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Abstract
The present study reports the formulation and evaluation of a natural chewing gum developed using a biodegradable resin–wax base enriched with immunomodulatory herbal constituents. The gum base was prepared using dammar resin, beeswax, and gum karaya, while jaggery was employed as a natural sweetener. A polyherbal blend comprising moringa, giloy, bael leaves, pomegranate peel, jamun leaves, guava leaves, curry leaves, marigold leaves, and chia seeds was incorporated to impart antioxidant and immunomodulatory properties. The formulation was optimized for texture, palatability, and stability. Physicochemical characterization, sensory evaluation, and in vitro antioxidant activity were assessed. The gum exhibited desirable elasticity, uniform distribution of actives, acceptable taste, and significant free radical scavenging activity. The developed formulation provides a novel, natural, and biodegradable chewing gum system for buccal delivery of phytoconstituents with potential applications in functional foods and nutraceuticals.
How to Cite this Paper
Badal, S. (2026). Development and Evaluation of a Natural Resin–Wax Based Herbal Chewing Gum as a Buccal Immunomodulatory Delivery System. International Journal of Creative and Open Research in Engineering and Management, <i>02</i>(05). https://doi.org/10.55041/ijcope.v2i5.439
Badal, Shelly. "Development and Evaluation of a Natural Resin–Wax Based Herbal Chewing Gum as a Buccal Immunomodulatory Delivery System." International Journal of Creative and Open Research in Engineering and Management, vol. 02, no. 05, 2026, pp. . doi:https://doi.org/10.55041/ijcope.v2i5.439.
Badal, Shelly. "Development and Evaluation of a Natural Resin–Wax Based Herbal Chewing Gum as a Buccal Immunomodulatory Delivery System." International Journal of Creative and Open Research in Engineering and Management 02, no. 05 (2026). https://doi.org/https://doi.org/10.55041/ijcope.v2i5.439.
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- •Published on: May 14 2026
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