Published on: May 2026
GLUCONOVA: A PHYTOENGINEERED PASSIFLORA EDULIS-BASED POLYHERBAL SYSTEM FOR PRECISION GLYCEMIC HOMEOSTASIS
Gourkar Khushi Sanjay Jogdand Akanksha Vinod Shirole Saloni
Dr. Tambe Sagar Eknath
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Abstract
Each constituent plant contributes a distinct pharmacological mechanism: Passiflora edulis leaves provide orientin, vitexin, and chrysin that exhibit insulin mimetic and beta-cell protective activity; Coccinia grandis supplies cucurbitacins and flavonoids that inhibit hepatic glucose output and enhance peripheral glucose utilization; and Nigella sativa contributes thymoquinone, which is renowned for its insulin-sensitizing, antioxidant, and anti-inflammatory properties. Together, these phytochemicals form a synergistic matrix targeting multiple nodes of glucose dysregulation, making GLUCONOVA a promising candidate for precision glycemic homeostasis.
Keywords: Passiflora edulis; Coccinia grandis; Nigella sativa; polyherbal formulation; Type 2 Diabetes Mellitus; glycemic control; thymoquinone; orientin; phytomedicine
How to Cite this Paper
Sanjay, G. K., Vinod, J. A. & Saloni, S. (2026). Gluconova: A Phytoengineered Passiflora Edulis-Based Polyherbal System for Precision Glycemic Homeostasis. International Journal of Creative and Open Research in Engineering and Management, <i>02</i>(05). https://doi.org/10.55041/ijcope.v2i5.775
Sanjay, Gourkar, et al.. "Gluconova: A Phytoengineered Passiflora Edulis-Based Polyherbal System for Precision Glycemic Homeostasis." International Journal of Creative and Open Research in Engineering and Management, vol. 02, no. 05, 2026, pp. . doi:https://doi.org/10.55041/ijcope.v2i5.775.
Sanjay, Gourkar,Jogdand Vinod, and Shirole Saloni. "Gluconova: A Phytoengineered Passiflora Edulis-Based Polyherbal System for Precision Glycemic Homeostasis." International Journal of Creative and Open Research in Engineering and Management 02, no. 05 (2026). https://doi.org/https://doi.org/10.55041/ijcope.v2i5.775.
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- •Published on: May 28 2026
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