Phytochemical Screening and Antibacterial Analysis of Calotropis Procera Flower Extracts

Muhammada, Ibrahim; Ahmada, Shamsuddeen Abdullahi

doi:https://doi.org/10.55041/ijcope.v2i7.174

Published on: July 2026

PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ANALYSIS OF CALOTROPIS PROCERA FLOWER EXTRACTS

Ibrahim Muhammada Shamsuddeen Abdullahi Ahmada

Department of Pure and Industrial Chemistry, Faculty of Science, Sokoto State University, Along Birnin Kebbi Road, Sokoto, P.M.B. 2134, Nigeria.

DOI:https://doi.org/10.55041/ijcope.v2i7.174

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Abstract

Medicinal plants containing active chemical constituents with high antibacterial property play an important role in new drugs discovery. In this study we have identified the various chemical compounds present in the flower extract of calotropis procera found in Sokoto region and also assessed its antibacterial activity against some selected bacterial strains for the possibility of using them in the development of new antibiotics to reduce cost of health care and mortality rate due to bacterial resistance. Cool extraction method was adopted to extract the flower of calotropis procera using three different solvent (n-hexane, chloroform and ethanol) and also standard methods were used to assess the antibacterial activity of the extracts. The result obtained from solvent extraction of calotropis procera flower revealed that n-hexane, chloroform and ethanol had a mass of 2.19 g, 0.9 g, 3.2 g, with percentage yield of 4.30 %, 2.35 % and 11.98 % respectively. The result of the extraction revealed that calotropis procera flower consists of more polar compounds than non-polar ones. The phytochemical screening of the flower extracts of calotropis procera revealed the presence of alkaloids, steroids and tannins while flavonoids, antharaquinones, saponins and cardiac glycoside were not detected. The results of the antibacterial studies revealed that all the fractions has activity on the selected bacteria strains (S. aureus, E. coli and Shagella) with zone of inhibition that ranges between 2-8 mm. these results shows that the calotropis procera flower has a potential for the development of new antibiotic drugs.

Keywords: Phytochemical Screening, Antibacterial Analysis, Antibioltics, Calotropis procera, Drug resistance

How to Cite this Paper

Muhammada, I. & Ahmada, S. A. (2026). Phytochemical Screening and Antibacterial Analysis of Calotropis Procera Flower Extracts. International Journal of Creative and Open Research in Engineering and Management, <i>02</i>(7), 1-9. https://doi.org/10.55041/ijcope.v2i7.174

Muhammada, Ibrahim, and Shamsuddeen Ahmada. "Phytochemical Screening and Antibacterial Analysis of Calotropis Procera Flower Extracts." International Journal of Creative and Open Research in Engineering and Management, vol. 02, no. 7, 2026, pp. 1-9. doi:https://doi.org/10.55041/ijcope.v2i7.174.

Muhammada, Ibrahim, and Shamsuddeen Ahmada. "Phytochemical Screening and Antibacterial Analysis of Calotropis Procera Flower Extracts." International Journal of Creative and Open Research in Engineering and Management 02, no. 7 (2026): 1-9. https://doi.org/https://doi.org/10.55041/ijcope.v2i7.174.

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