Published on: December 2025
ASSESSMENT OF ANTIBIOTIC PRESCRIBING PATTERNS AND ANTIMICROBIAL RESISTANCE IN TERTIARY CARE HOSPITALS
Sneha R. Pawar Kiran V. Shinde
Dr. Sandeep V. Kulkarni
Shree Lakshmi College of Pharmacy
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Abstract
Antimicrobial resistance (AMR) has emerged as a global public health threat, particularly within tertiary care hospitals where high patient turnover and intensive antibiotic use create high selective pressure for resistant organisms. This study investigates antibiotic prescribing patterns and the prevalence of antimicrobial resistance in tertiary care settings, analyzing prescribing trends, appropriateness of antibiotic use, and patterns of resistance among common bacterial pathogens. The cross-sectional design included prescription audits, laboratory surveillance data, and clinician interviews across three tertiary care hospitals. The findings reveal significant inconsistencies in antibiotic use relative to established guidelines, high rates of broad-spectrum antibiotic prescriptions, and escalating resistance rates in pathogens such as Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus. The presence of multidrug-resistant organisms (MDROs) demonstrates an urgent need for strengthened antimicrobial stewardship programs (ASPs), enhanced laboratory capacity for culture and sensitivity testing, and continuous physician education on prudent antibiotic use. This research reinforces that targeted interventions and policy implementations at the institutional level are imperative to curb inappropriate antibiotic use and mitigate the impact of AMR.
Keywords: Antimicrobial resistance, antibiotic prescribing patterns, tertiary care hospitals, antimicrobial stewardship, multidrug resistance.
How to Cite this Paper
Pawar, S. R. & Shinde, K. V. (2025). Assessment of Antibiotic Prescribing Patterns and Antimicrobial Resistance in Tertiary Care Hospitals. International Journal of Creative and Open Research in Engineering and Management, <i>01</i>(03), 1-9. https://doi.org/10.55041/ijcope.v1i3.003
Pawar, Sneha, and Kiran Shinde. "Assessment of Antibiotic Prescribing Patterns and Antimicrobial Resistance in Tertiary Care Hospitals." International Journal of Creative and Open Research in Engineering and Management, vol. 01, no. 03, 2025, pp. 1-9. doi:https://doi.org/10.55041/ijcope.v1i3.003.
Pawar, Sneha, and Kiran Shinde. "Assessment of Antibiotic Prescribing Patterns and Antimicrobial Resistance in Tertiary Care Hospitals." International Journal of Creative and Open Research in Engineering and Management 01, no. 03 (2025): 1-9. https://doi.org/https://doi.org/10.55041/ijcope.v1i3.003.
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- •Published on: Dec 23 2025
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