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International Journal of Creative and Open Research in Engineering and Management

A Peer-Reviewed, Open-Access International Journal Supporting Multidisciplinary Research, Digital Publishing Standards, DOI Registration, and Academic Indexing.
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ISSN: 3108-1754 (Online)
Crossref DOI: Available
ISO Certification: 9001:2015
Publication Fee: 599/- INR
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License: CC BY 4.0
Peer Review: Double Blind
Volume 02, Issue 8

Published on: August 2026

BREAST CANCER CLASSIFICATION USING LOGISTIC REGRESSION ON MORPHOMETRIC FEATURES FROM FINE-NEEDLE ASPIRATION: A COMPREHENSIVE MACHINE LEARNING FRAMEWORK

PRASANTH D HANUSH SHANDILYA R

Assistant Professor, Department of Information Technology and Cognitive Systems, Sri krishna College of Arts and College, Coimbatore, India.

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Plagiarism Passed Peer Reviewed Open Access

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Abstract

Breast cancer remains one of the leading causes of cancer-related mortality among women worldwide. Early and accurate differentiation between benign and malignant tumors is critical for improving patient outcomes. This paper presents a complete machine-learning pipeline for binary classification of breast masses using the Wisconsin Breast Cancer Diagnostic (WBCD) dataset. Features describing cell nuclei morphology (mean, standard error, and worst values of radius, texture, perimeter, area, smoothness, compactness, concavity, concave points, symmetry, and fractal dimension) are extracted from digitized fine-needle aspirate (FNA) images. After rigorous preprocessing that includes standardization and exploratory correlation analysis, a logistic regression classifier is trained. The model achieves 94.73% accuracy on the training set and 92.11% accuracy on an independent 20% hold-out test set, together with balanced precision, recall, and F1-score. Comprehensive mathematical formulations of the sigmoid hypothesis, binary cross-entropy loss, gradient-based parameter estimation, and standard evaluation metrics are provided. Comparative experiments against support-vector machines, random forests, and k-nearest neighbors confirm that logistic regression offers an attractive trade-off between predictive performance, interpretability, and computational efficiency. Feature-importance analysis highlights mean concave points, worst radius, and worst perimeter as the most discriminative attributes. The proposed framework is fully reproducible, clinically interpretable, and suitable for integration into computer-aided diagnosis systems.

How to Cite this Paper

D, P. & R, H. S. (2026). Breast Cancer Classification Using Logistic Regression on Morphometric Features from Fine-Needle Aspiration: A Comprehensive Machine Learning Framework. International Journal of Creative and Open Research in Engineering and Management, <i>02</i>(8), 1-9. https://doi.org/10.55041/ijcope.v2i8.061

D, PRASANTH, and HANUSH R. "Breast Cancer Classification Using Logistic Regression on Morphometric Features from Fine-Needle Aspiration: A Comprehensive Machine Learning Framework." International Journal of Creative and Open Research in Engineering and Management, vol. 02, no. 8, 2026, pp. 1-9. doi:https://doi.org/10.55041/ijcope.v2i8.061.

D, PRASANTH, and HANUSH R. "Breast Cancer Classification Using Logistic Regression on Morphometric Features from Fine-Needle Aspiration: A Comprehensive Machine Learning Framework." International Journal of Creative and Open Research in Engineering and Management 02, no. 8 (2026): 1-9. https://doi.org/https://doi.org/10.55041/ijcope.v2i8.061.

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References


  • H. Wolberg, W. N. Street, and O. L. Mangasarian, “Breast cancer Wisconsin (diagnostic) data set,” UCI Machine Learning Repository, 1995.

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  • Li et al., “Deep learning based breast cancer detection,” IEEE Access, 2021–2024 series of works.

  • Recent IEEE Conference papers (2023–2025) on Optuna-optimized logistic regression, SMOTE-enhanced LR, and comparative studies using the Wisconsin Breast Cancer Diagnostic dataset (CSITSS, DECoN, INMIC, ICECA, i-COSTE, etc.).

  • A. Spanhol et al., “A dataset for breast cancer histopathological image classification,” IEEE Trans. Biomed. Eng., 2016.

  • Multiple comparative studies (2022–2025) reporting logistic regression accuracies in the range 95–98% on WBCD with various preprocessing and validation schemes.

  • Sharma et al., “Explainable AI approaches for breast cancer diagnosis using SHAP and LIME,” recent IEEE and Springer publications, 2024–2025.

  • Scikit-learn documentation and open-source implementations of logistic regression, SVM, random forest, and k-NN

Ethical Compliance & Review Process

  • All submissions are screened under plagiarism detection.
  • Review follows editorial policy.
  • Authors retain copyright.
  • Peer Review Type: Double-Blind Peer Review
  • Published on: Aug 08 2026
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