This study presents a systematic review and quantitative evidence synthesis of climate-sensitive health risks based on peer-reviewed literature published between 2010 and 2025. A PRISMA-inspired approach was used to screen 72 studies, of which 65 met inclusion criteria. The analysis integrates effect sizes, vote-counting, and regional comparisons to quantify relationships between climate exposures and health outcomes. Findings indicate that heat exposure is associated with an approximate 8–15% increase in mortality per 1°C rise. Vector-borne diseases show consistent geographic expansion, while air pollution contributes significantly to respiratory morbidity. An India-focused segment contextualizes these findings within national vulnerability patterns. The study contributes a structured analytical and policy framework for strengthening climate-resilient health systems.

Keywords: Climate Change, Public Health, Heat Stress, Evidence Synthesis, Health Systems