The present study was aimed at the formulation and evaluation of a herbal pain relief cream containing clove oil, menthol, and camphor. Herbal topical formulations have gained considerable importance due to their safety, effectiveness, and reduced side effects compared to synthetic formulations. Clove oil possesses potent analgesic and anti-inflammatory properties due to the presence of eugenol, menthol provides a cooling sensation and counterirritant action, while camphor improves blood circulation and provides soothing pain relief. The cream was prepared using the fusion method with suitable excipients such as beeswax, liquid paraffin, borax, and preservatives. The prepared formulation was evaluated for various physicochemical parameters including appearance, pH, spreadability, homogeneity, washability, irritancy, viscosity, consistency, and stability studies. The formulation showed satisfactory results with good spreadability, skin-friendly pH, excellent homogeneity, stability, and absence of irritation. The synergistic action of clove oil, menthol, and camphor provided effective analgesic and anti-inflammatory activity. The study concluded that the developed herbal pain relief cream can be considered a safe, economical, and effective alternative to synthetic pain relief formulations for topical management of pain and inflammation.¹²

Keywords: Herbal cream; Clove oil; Menthol; Camphor; Analgesic; Topical formulation